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Nogo Receptor Interacts with Brain APP and Aβ to Reduce Pathologic Changes in Alzheimer’s Transgenic Mice
Pathophysiologic hypotheses for Alzheimer’s disease (AD) are centered on the role of the amyloid plaque Aβ peptide and the mechanism of its derivation from the amyloid precursor protein (APP). As part of the disease process, an aberrant axonai sprouting response is known to occur near Aβ deposits. A...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2846284/ https://ncbi.nlm.nih.gov/pubmed/18220524 |
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