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Nogo Receptor Interacts with Brain APP and Aβ to Reduce Pathologic Changes in Alzheimer’s Transgenic Mice

Pathophysiologic hypotheses for Alzheimer’s disease (AD) are centered on the role of the amyloid plaque Aβ peptide and the mechanism of its derivation from the amyloid precursor protein (APP). As part of the disease process, an aberrant axonai sprouting response is known to occur near Aβ deposits. A...

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Bibliografiske detaljer
Main Authors: Park, James H., Strittmatter, Stephen M.
Format: Artigo
Sprog:Inglês
Udgivet: 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2846284/
https://ncbi.nlm.nih.gov/pubmed/18220524
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