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Nogo Receptor Interacts with Brain APP and Aβ to Reduce Pathologic Changes in Alzheimer’s Transgenic Mice

Pathophysiologic hypotheses for Alzheimer’s disease (AD) are centered on the role of the amyloid plaque Aβ peptide and the mechanism of its derivation from the amyloid precursor protein (APP). As part of the disease process, an aberrant axonai sprouting response is known to occur near Aβ deposits. A...

詳細記述

保存先:
書誌詳細
主要な著者: Park, James H., Strittmatter, Stephen M.
フォーマット: Artigo
言語:Inglês
出版事項: 2007
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2846284/
https://ncbi.nlm.nih.gov/pubmed/18220524
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