Reduced β-amyloid pathology in an APP transgenic mouse model of Alzheimer’s disease lacking functional B and T cells

INTRODUCTION: In Alzheimer’s disease, accumulation and pathological aggregation of amyloid β-peptide is accompanied by the induction of complex immune responses, which have been attributed both beneficial and detrimental properties. Such responses implicate various cell types of the innate and adapt...

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Detalhes bibliográficos
Publicado no:Acta Neuropathol Commun
Main Authors: Späni, Claudia, Suter, Tobias, Derungs, Rebecca, Ferretti, Maria Teresa, Welt, Tobias, Wirth, Fabian, Gericke, Christoph, Nitsch, Roger M., Kulic, Luka
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4642668/
https://ncbi.nlm.nih.gov/pubmed/26558367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-015-0251-x
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