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Subcutaneous Nogo Receptor Removes Brain Amyloid-β and Improves Spatial Memory in Alzheimer's Transgenic Mice

The production and aggregation of cerebral amyloid-β (Aβ) peptide are thought to play a causal role in Alzheimer's disease (AD). Previously, we found that the Nogo-66 receptor (NgR) interacts physically with both Aβ and the amyloid precursor protein (APP). The inverse correlation of Aβ levels w...

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Detalhes bibliográficos
Main Authors: Park, James H., Widi, Gabriel A., Gimbel, David A., Harel, Noam Y., Lee, Daniel H. S., Strittmatter, Stephen M.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2856604/
https://ncbi.nlm.nih.gov/pubmed/17182778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4504-06.2006
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