Nalaganje...
Alternative splicing of NaV1.7 exon 5 increases the impact of the painful PEPD mutant channel I1461T
Alternative splicing is known to alter pharmacological sensitivities, kinetics, channel distribution under pathological conditions, and developmental regulation of VGSCs. Mutations that alter channel properties in NaV1.7 have been genetically implicated in patients with bouts of extreme pain classif...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2009
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2856339/ https://ncbi.nlm.nih.gov/pubmed/19633428 |
| Oznake: |
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