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Intrinsic Determinants of Neurotoxic Aggregate Formation by the Amyloid β Peptide
The extent to which proteins aggregate into distinct structures ranging from prefibrillar oligomers to amyloid fibrils is key to the pathogenesis of many age-related degenerative diseases. We describe here for the Alzheimer's disease-related amyloid β peptide (Aβ) an investigation of the sequen...
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Autores principales: | , , , , , , , , , , , |
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Formato: | Artigo |
Lenguaje: | Inglês |
Publicado: |
The Biophysical Society
2010
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Materias: | |
Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2856165/ https://ncbi.nlm.nih.gov/pubmed/20409489 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.12.4320 |
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