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Prefibrillar Amyloid Aggregates Could Be Generic Toxins in Higher Organisms

More than 40 human diseases are associated with fibrillar deposits of specific peptides or proteins in tissue. Amyloid fibrils, or their precursors, can be highly toxic to cells, suggesting their key role in disease pathogenesis. Proteins not associated with any disease are able to form oligomers an...

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Bibliografske podrobnosti
izdano v:J Neurosci
Main Authors: Baglioni, Serena, Casamenti, Fiorella, Bucciantini, Monica, Luheshi, Leila M., Taddei, Niccolò, Chiti, Fabrizio, Dobson, Christopher M., Stefani, Massimo
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2006
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Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6673784/
https://ncbi.nlm.nih.gov/pubmed/16885229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4809-05.2006
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