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Prefibrillar Amyloid Aggregates Could Be Generic Toxins in Higher Organisms
More than 40 human diseases are associated with fibrillar deposits of specific peptides or proteins in tissue. Amyloid fibrils, or their precursors, can be highly toxic to cells, suggesting their key role in disease pathogenesis. Proteins not associated with any disease are able to form oligomers an...
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| Pubblicato in: | J Neurosci |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Society for Neuroscience
2006
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6673784/ https://ncbi.nlm.nih.gov/pubmed/16885229 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4809-05.2006 |
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