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Prefibrillar Amyloid Aggregates Could Be Generic Toxins in Higher Organisms

More than 40 human diseases are associated with fibrillar deposits of specific peptides or proteins in tissue. Amyloid fibrils, or their precursors, can be highly toxic to cells, suggesting their key role in disease pathogenesis. Proteins not associated with any disease are able to form oligomers an...

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Bibliografische gegevens
Gepubliceerd in:J Neurosci
Hoofdauteurs: Baglioni, Serena, Casamenti, Fiorella, Bucciantini, Monica, Luheshi, Leila M., Taddei, Niccolò, Chiti, Fabrizio, Dobson, Christopher M., Stefani, Massimo
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Society for Neuroscience 2006
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6673784/
https://ncbi.nlm.nih.gov/pubmed/16885229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4809-05.2006
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