Nonspecific Interaction of Prefibrillar Amyloid Aggregates with Glutamatergic Receptors Results in Ca(2+) Increase in Primary Neuronal Cells

It is widely reported that the Ca(2+) increase following nonspecific cell membrane permeabilization is among the earliest biochemical modifications in cells exposed to toxic amyloid aggregates. However, more recently receptors with Ca(2+) channel activity such as α-amino-3-hydroxy-5-methylisoxazole-...

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Autores principales: Pellistri, Francesca, Bucciantini, Monica, Relini, Annalisa, Nosi, Daniele, Gliozzi, Alessandra, Robello, Mauro, Stefani, Massimo
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2008
Materias:
Membrane Transport, Structure, Function, and Biogenesis
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2662062/
https://ncbi.nlm.nih.gov/pubmed/18676369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M803992200
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