The Amphipathic GM1 Molecule Stabilizes Amyloid Aggregates, Preventing their Cytotoxicity

Amyloid aggregates have been demonstrated to exert cytotoxic effects in several diseases. It is widely accepted that the complex and fascinating aggregation pathway involves a series of steps during which many heterogeneous intermediates are generated. This process may be greatly potentiated by the...

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Vydáno v:Biophys J
Hlavní autoři: Bucciantini, Monica, Leri, Manuela, Stefani, Massimo, Melki, Ronald, Zecchi-Orlandini, Sandra, Nosi, Daniele
Médium: Artigo
Jazyk:Inglês
Vydáno: The Biophysical Society 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7376221/
https://ncbi.nlm.nih.gov/pubmed/32579964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2020.06.005
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