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The Amphipathic GM1 Molecule Stabilizes Amyloid Aggregates, Preventing their Cytotoxicity

Amyloid aggregates have been demonstrated to exert cytotoxic effects in several diseases. It is widely accepted that the complex and fascinating aggregation pathway involves a series of steps during which many heterogeneous intermediates are generated. This process may be greatly potentiated by the...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Biophys J
Prif Awduron: Bucciantini, Monica, Leri, Manuela, Stefani, Massimo, Melki, Ronald, Zecchi-Orlandini, Sandra, Nosi, Daniele
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Biophysical Society 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7376221/
https://ncbi.nlm.nih.gov/pubmed/32579964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2020.06.005
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