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Natively Folded HypF-N and Its Early Amyloid Aggregates Interact with Phospholipid Monolayers and Destabilize Supported Phospholipid Bilayers

Recent data depict membranes as the main sites where proteins/peptides are recruited and concentrated, misfold, and nucleate amyloids; at the same time, membranes are considered key triggers of amyloid toxicity. The N-terminal domain of the prokaryotic hydrogenase maturation factor HypF (HypF-N) in...

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Detalhes bibliográficos
Main Authors: Canale, Claudio, Torrassa, Silvia, Rispoli, Pasquale, Relini, Annalisa, Rolandi, Ranieri, Bucciantini, Monica, Stefani, Massimo, Gliozzi, Alessandra
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1779933/
https://ncbi.nlm.nih.gov/pubmed/16997875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.089482
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