Interaction of toxic and non-toxic HypF-N oligomers with lipid bilayers investigated at high resolution with atomic force microscopy

Protein misfolded oligomers are considered the most toxic species amongst those formed in the process of amyloid formation and the molecular basis of their toxicity, although not completely understood, is thought to originate from the interaction with the cellular membrane. Here, we sought to highli...

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Udgivet i:Oncotarget
Main Authors: Oropesa-Nuñez, Reinier, Seghezza, Silvia, Dante, Silvia, Diaspro, Alberto, Cascella, Roberta, Cecchi, Cristina, Stefani, Massimo, Chiti, Fabrizio, Canale, Claudio
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
Fag:
Research Paper: Neuroscience
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5216700/
https://ncbi.nlm.nih.gov/pubmed/27391440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10449
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