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Assessing the role of aromatic residues in the amyloid aggregation of human muscle acylphosphatase
Among the many parameters that have been proposed to promote amyloid fibril formation is the π-stacking of aromatic residues. We have studied the amyloid aggregation of several mutants of human muscle acylphosphatase in which an aromatic residue was substituted with a non-aromatic one. The aggregati...
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Médium: | Artigo |
Jazyk: | Inglês |
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Cold Spring Harbor Laboratory Press
2006
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On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2242477/ https://ncbi.nlm.nih.gov/pubmed/16600970 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.051915806 |
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