Investigation of Trypanothione Reductase as a Drug Target in Trypanosoma brucei

There is an urgent need for new drugs for the treatment of tropical parasitic diseases such as human African trypanosomiasis, which is caused by Trypanosoma brucei. The enzyme trypanothione reductase (TryR) is a potential drug target within these organisms. Herein we report the screening of a 62000...

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Bibliographische Detailangaben
Hauptverfasser: Spinks, Daniel, Shanks, Emma J, Cleghorn, Laura A T, McElroy, Stuart, Jones, Deuan, James, Daniel, Fairlamb, Alan H, Frearson, Julie A, Wyatt, Paul G, Gilbert, Ian H
Format: Artigo
Sprache:Inglês
Veröffentlicht: WILEY-VCH Verlag 2009
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2855869/
https://ncbi.nlm.nih.gov/pubmed/19924760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.200900262
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