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Alternate Strategies of Hsp90 Modulation for the Treatment of Cancer and Other Diseases
The 90 kDa heat shock protein (Hsp90) has become a validated target for the development of anti-cancer agents. Several Hsp90 inhibitors are currently under clinical trial investigation for the treatment of cancer. All of these agents inhibit Hsp90’s protein folding activity by binding to the N-termi...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2853258/ https://ncbi.nlm.nih.gov/pubmed/19860731 |
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