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Cruentaren A Binds F(1)F(0) ATP Synthase To Modulate the Hsp90 Protein Folding Machinery
[Image: see text] The molecular chaperone Hsp90 requires the assistance of immunophilins, co-chaperones, and partner proteins for the conformational maturation of client proteins. Hsp90 inhibition represents a promising anticancer strategy due to the dependence of numerous oncogenic signaling pathwa...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American
Chemical
Society
2014
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4090037/ https://ncbi.nlm.nih.gov/pubmed/24450340 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb400906e |
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