A Systematic Protocol for the Characterization of Hsp90 Modulators

Several Hsp90 modulators have been identified including the N-terminal ligand geldanamycin (GDA), the C-terminal ligand novobiocin (NB), and the co-chaperone disruptor celastrol. Other Hsp90 modulators elicit a mechanism of action that remains unknown. For example, the natural product gedunin and th...

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Bibliografski detalji
Izdano u:Bioorg Med Chem
Glavni autori: Matts, Robert L., Brandt, Gary E. L., Lu, Yuanming, Dixit, Anshuman, Mollapour, Mehdi, Wang, Suiquan, Donnelly, Alison C., Neckers, Leonard, Verkhivker, Gennady, Blagg, Brian S. J.
Format: Artigo
Jezik:Inglês
Izdano: 2010
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4618652/
https://ncbi.nlm.nih.gov/pubmed/21129982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2010.10.029
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