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Probing Molecular Mechanisms of the Hsp90 Chaperone: Biophysical Modeling Identifies Key Regulators of Functional Dynamics

Deciphering functional mechanisms of the Hsp90 chaperone machinery is an important objective in cancer biology aiming to facilitate discovery of targeted anti-cancer therapies. Despite significant advances in understanding structure and function of molecular chaperones, organizing molecular principl...

詳細記述

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書誌詳細
主要な著者: Dixit, Anshuman, Verkhivker, Gennady M.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3356286/
https://ncbi.nlm.nih.gov/pubmed/22624053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037605
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