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Probing Molecular Mechanisms of the Hsp90 Chaperone: Biophysical Modeling Identifies Key Regulators of Functional Dynamics
Deciphering functional mechanisms of the Hsp90 chaperone machinery is an important objective in cancer biology aiming to facilitate discovery of targeted anti-cancer therapies. Despite significant advances in understanding structure and function of molecular chaperones, organizing molecular principl...
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Glavni autori: | , |
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Format: | Artigo |
Jezik: | Inglês |
Izdano: |
Public Library of Science
2012
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Teme: | |
Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3356286/ https://ncbi.nlm.nih.gov/pubmed/22624053 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037605 |
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