Efficient integration of transgenes into a defined locus in human embryonic stem cells

Random integration is one of the more straightforward methods to introduce a transgene into human embryonic stem (ES) cells. However, random integration may result in transgene silencing and altered cell phenotype due to insertional mutagenesis in undefined gene regions. Moreover, reliability of dat...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Sakurai, Kenji, Shimoji, Miho, Tahimic, Candice G. T., Aiba, Kazuhiro, Kawase, Eihachiro, Hasegawa, Kouichi, Amagai, Yuji, Suemori, Hirofumi, Nakatsuji, Norio
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2010
Gaiak:
Methods Online
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2853137/
https://ncbi.nlm.nih.gov/pubmed/20071742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp1234
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