Overexpression of Nuclear Receptor 5A1 Induces and Maintains an Intermediate State of Conversion between Primed and Naive Pluripotency

Naive and primed human pluripotent stem cells (hPSCs) have provided useful insights into the regulation of pluripotency. However, the molecular mechanisms regulating naive conversion remain elusive. Here, we report intermediate naive conversion induced by overexpressing nuclear receptor 5A1 (NR5A1)...

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Udgivet i:Stem Cell Reports
Main Authors: Yamauchi, Kaori, Ikeda, Tatsuhiko, Hosokawa, Mihoko, Nakatsuji, Norio, Kawase, Eihachiro, Chuma, Shinichiro, Hasegawa, Kouichi, Suemori, Hirofumi
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7066342/
https://ncbi.nlm.nih.gov/pubmed/32084386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2020.01.012
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