Overexpression of Nuclear Receptor 5A1 Induces and Maintains an Intermediate State of Conversion between Primed and Naive Pluripotency

Naive and primed human pluripotent stem cells (hPSCs) have provided useful insights into the regulation of pluripotency. However, the molecular mechanisms regulating naive conversion remain elusive. Here, we report intermediate naive conversion induced by overexpressing nuclear receptor 5A1 (NR5A1)...

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Publicat a:Stem Cell Reports
Autors principals: Yamauchi, Kaori, Ikeda, Tatsuhiko, Hosokawa, Mihoko, Nakatsuji, Norio, Kawase, Eihachiro, Chuma, Shinichiro, Hasegawa, Kouichi, Suemori, Hirofumi
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7066342/
https://ncbi.nlm.nih.gov/pubmed/32084386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2020.01.012
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