The ribosome assembly factor Nep1 responsible for Bowen–Conradi syndrome is a pseudouridine-N1-specific methyltransferase

Podobne zapisy

• The Bowen–Conradi syndrome protein Nep1 (Emg1) has a dual role in eukaryotic ribosome biogenesis, as an essential assembly factor and in the methylation of Ψ1191 in yeast 18S rRNA
  od: Meyer, Britta, i wsp.
  Wydane: (2011)
• Identification of the enzyme responsible for N1-methylation of pseudouridine 54 in archaeal tRNAs
  od: Wurm, Jan Philip, i wsp.
  Wydane: (2012)
• The crystal structure of Nep1 reveals an extended SPOUT-class methyltransferase fold and a pre-organized SAM-binding site
  od: Taylor, Alexander B., i wsp.
  Wydane: (2008)
• Mutation of a Gene Essential for Ribosome Biogenesis, EMG1, Causes Bowen-Conradi Syndrome
  od: Armistead, Joy, i wsp.
  Wydane: (2009)
• Structural insight into the functional mechanism of Nep1/Emg1 N1-specific pseudouridine methyltransferase in ribosome biogenesis
  od: Thomas, Seth R., i wsp.
  Wydane: (2011)