The ribosome assembly factor Nep1 responsible for Bowen–Conradi syndrome is a pseudouridine-N1-specific methyltransferase

Lignende værker

• The Bowen–Conradi syndrome protein Nep1 (Emg1) has a dual role in eukaryotic ribosome biogenesis, as an essential assembly factor and in the methylation of Ψ1191 in yeast 18S rRNA
  af: Meyer, Britta, et al.
  Udgivet: (2011)
• Identification of the enzyme responsible for N1-methylation of pseudouridine 54 in archaeal tRNAs
  af: Wurm, Jan Philip, et al.
  Udgivet: (2012)
• The crystal structure of Nep1 reveals an extended SPOUT-class methyltransferase fold and a pre-organized SAM-binding site
  af: Taylor, Alexander B., et al.
  Udgivet: (2008)
• Mutation of a Gene Essential for Ribosome Biogenesis, EMG1, Causes Bowen-Conradi Syndrome
  af: Armistead, Joy, et al.
  Udgivet: (2009)
• Identification of a novel methyltransferase, Bmt2, responsible for the N-1-methyl-adenosine base modification of 25S rRNA in Saccharomyces cerevisiae
  af: Sharma, Sunny, et al.
  Udgivet: (2013)