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Identification of the enzyme responsible for N1-methylation of pseudouridine 54 in archaeal tRNAs

tRNAs from all three kingdoms of life contain a variety of modified nucleotides required for their stability, proper folding, and accurate decoding. One prominent example is the eponymous ribothymidine (rT) modification at position 54 in the T-arm of eukaryotic and bacterial tRNAs. In contrast, in m...

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Autors principals: Wurm, Jan Philip, Griese, Marco, Bahr, Ute, Held, Martin, Heckel, Alexander, Karas, Michael, Soppa, Jörg, Wöhnert, Jens
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3285930/
https://ncbi.nlm.nih.gov/pubmed/22274954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.028498.111
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