Structural insight into the functional mechanism of Nep1/Emg1 N1-specific pseudouridine methyltransferase in ribosome biogenesis

Nucleolar Essential Protein 1 (Nep1) is required for small subunit (SSU) ribosomal RNA (rRNA) maturation and is mutated in Bowen–Conradi Syndrome. Although yeast (Saccharomyces cerevisiae) Nep1 interacts with a consensus sequence found in three regions of SSU rRNA, the molecular details of the inter...

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Hlavní autoři: Thomas, Seth R., Keller, Christopher A., Szyk, Agnieszka, Cannon, Joe R., LaRonde-LeBlanc, Nicole A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2011
Témata:
Structural Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064781/
https://ncbi.nlm.nih.gov/pubmed/21087996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq1131
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