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Structural determinants in phycotoxins and AChBP conferring high affinity binding and nicotinic AChR antagonism
Spirolide and gymnodimine macrocyclic imine phycotoxins belong to an emerging class of chemical agents associated with marine algal blooms and shellfish toxicity. Analysis of 13-desmethyl spirolide C and gymnodimine A by binding and voltage-clamp recordings on muscle-type α1(2)βγδ and neuronal α3β2...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2851920/ https://ncbi.nlm.nih.gov/pubmed/20224036 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0912372107 |
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