Atomic interactions of neonicotinoid agonists with AChBP: Molecular recognition of the distinctive electronegative pharmacophore

Acetylcholine-binding proteins (AChBPs) from mollusks are suitable structural and functional surrogates of the nicotinic acetylcholine receptors when combined with transmembrane spans of the nicotinic receptor. These proteins assemble as a pentamer with identical ACh binding sites at the subunit int...

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Hlavní autoři: Talley, Todd T., Harel, Michal, Hibbs, Ryan E., Radić, Zoran, Tomizawa, Motohiro, Casida, John E., Taylor, Palmer
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2008
Témata:
Physical Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2396707/
https://ncbi.nlm.nih.gov/pubmed/18477694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0802197105
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