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Crystal structure of a Cbtx–AChBP complex reveals essential interactions between snake α-neurotoxins and nicotinic receptors

The crystal structure of the snake long α-neurotoxin, α-cobratoxin, bound to the pentameric acetylcholine-binding protein (AChBP) from Lymnaea stagnalis, was solved from good quality density maps despite a 4.2 Å overall resolution. The structure unambiguously reveals the positions and orientations o...

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Main Authors: Bourne, Yves, Talley, Todd T, Hansen, Scott B, Taylor, Palmer, Marchot, Pascale
Formato: Artigo
Idioma:Inglês
Publicado: 2005
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1142565/
https://ncbi.nlm.nih.gov/pubmed/15791209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600620
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