Marine macrocyclic imines, pinnatoxins A and G: structural determinants and functional properties to distinguish neuronal α7 from muscle α1(2)βγδ nAChRs

Pinnatoxins are macrocyclic imine phycotoxins associated with algal blooms and shellfish toxicity. Functional analysis of pinnatoxin-A and pinnatoxin-G, by binding and electrophysiology on membrane-embedded neuronal α7, α4β2 and α3β2 and muscle-type α1(2)βγδ nicotinic acetylcholine receptors (nAChRs...

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Publicado no:Structure
Main Authors: Bourne, Yves, Sulzenbacher, Gerlind, Radiæ, Zoran, Aráoz, Rómulo, Reynaud, Morgane, Benoit, Evelyne, Zakarian, Armen, Servent, Denis, Molgó, Jordi, Taylor, Palmer, Marchot, Pascale
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4461042/
https://ncbi.nlm.nih.gov/pubmed/26004441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2015.04.009
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