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Stability of Cyclic Imine Toxins: Interconversion of Pinnatoxin Amino Ketone and Pinnatoxin A in Aqueous Media

Pinnatoxins belong to the cyclic imine (CI) group of marine toxins with a unique toxicological profile. The need for structural integrity of the aliphatic 7-membered cyclic imine for the potent bioactivity of pinnatoxins has been experimentally demonstrated. In this study, we probe interconversion o...

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Hlavní autoři: Jackson, Jeffrey J., Stivala, Craig E., Iorga, Bogdan I., Molgó, Jordi, Zakarian, Armen
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4117372/
https://ncbi.nlm.nih.gov/pubmed/23116445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo301632d
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