Synthetic Pinnatoxins A and G Reversibly Block Mouse Skeletal Neuromuscular Transmission In Vivo and In Vitro

Pinnatoxins (PnTXs) A-H constitute an emerging family belonging to the cyclic imine group of phycotoxins. Interest has been focused on these fast-acting and highly-potent toxins because they are widely found in contaminated shellfish. Despite their highly complex molecular structure, PnTXs have been...

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Bibliographic Details
Published in:Mar Drugs
Main Authors: Benoit, Evelyne, Couesnon, Aurélie, Lindovsky, Jiri, Iorga, Bogdan I., Aráoz, Rómulo, Servent, Denis, Zakarian, Armen, Molgó, Jordi
Format: Artigo
Language:Inglês
Published: MDPI 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6562580/
https://ncbi.nlm.nih.gov/pubmed/31137661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md17050306
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