Wordt geladen...
Mutant APH(2″)-IIa Enzymes with Increased Activity against Amikacin and Isepamicin
Directed evolution by random PCR mutagenesis of the gene for the aminoglycoside 2″-IIa phosphotransferase generated R92H/D268N and N196D/D268N mutant enzymes, resulting in elevated levels of resistance to amikacin and isepamicin but not to other aminoglycoside antibiotics. Increases in the activitie...
Bewaard in:
| Hoofdauteurs: | , , , , |
|---|---|
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Society for Microbiology (ASM)
2010
|
| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2849353/ https://ncbi.nlm.nih.gov/pubmed/20145089 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01444-09 |
| Tags: |
Voeg label toe
Geen labels, Wees de eerste die dit record labelt!
|