Loading...

Structure of the phosphotransferase domain of the bifunctional aminoglycoside-resistance enzyme AAC(6′)-Ie-APH(2′′)-Ia

The bifunctional acetyltransferase(6′)-Ie-phosphotransfer­ase(2′′)-Ia [AAC(6′)-Ie-APH(2′′)-Ia] is the most important aminoglycoside-resistance enzyme in Gram-positive bacteria, conferring resistance to almost all known aminoglycoside antibiotics in clinical use. Owing to its importance, this enzyme...

Full description

Saved in:
Bibliographic Details
Main Authors: Smith, Clyde A., Toth, Marta, Bhattacharya, Monolekha, Frase, Hilary, Vakulenko, Sergei B.
Format: Artigo
Language:Inglês
Published: International Union of Crystallography 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4051501/
https://ncbi.nlm.nih.gov/pubmed/24914967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1399004714005331
Tags: Add Tag
No Tags, Be the first to tag this record!