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AN ANTIBIOTIC-RESISTANCE ENZYME FROM A DEEP-SEA BACTERIUM

We describe herein a highly proficient class A β-lactamase OIH-1 from the bacterium Oceanobacillus iheyensis, whose habitat is the sediment at a depth of 1050 meters in the Pacific Ocean. The OIH-1 structure was solved by molecular replacement and refined at 1.25 Å resolution. OIH-1 has evolved to b...

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Detalhes bibliográficos
Main Authors: Toth, Marta, Smith, Clyde, Frase, Hilary, Mobashery, Shahriar, Vakulenko, Sergei
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2826318/
https://ncbi.nlm.nih.gov/pubmed/20000704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja908850p
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