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Phospholemman Modulates the Gating of Cardiac L-Type Calcium Channels

Ca(2+) entry through L-type calcium channels (Ca(V)1.2) is critical in shaping the cardiac action potential and initiating cardiac contraction. Modulation of Ca(V)1.2 channel gating directly affects myocyte excitability and cardiac function. We have found that phospholemman (PLM), a member of the FX...

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Main Authors: Wang, Xianming, Gao, Guofeng, Guo, Kai, Yarotskyy, Viktor, Huang, Congxin, Elmslie, Keith S., Peterson, Blaise Z.
Formáid: Artigo
Teanga:Inglês
Foilsithe: The Biophysical Society 2010
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2849072/
https://ncbi.nlm.nih.gov/pubmed/20371314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.11.032
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