Regulation of L-type calcium channel by phospholemman in cardiac myocytes

We evaluated whether phospholemman (PLM) regulates L-type Ca(2+) current (I(Ca)) in mouse ventricular myocytes. Expression of α(1)-subunit of L-type Ca(2+) channels between wild-type (WT) and PLM knockout (KO) hearts was similar. Compared to WT myocytes, peak I(Ca) (at −10 mV) from KO myocytes was ~...

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Publicado no:J Mol Cell Cardiol
Main Authors: Zhang, Xue-Qian, Wang, JuFang, Song, Jianliang, Rabinowitz, Joseph, Chen, Xiongwen, Houser, Steven R., Peterson, Blaise Z., Tucker, Amy L., Feldman, Arthur M., Cheung, Joseph Y.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4468006/
https://ncbi.nlm.nih.gov/pubmed/25918050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2015.04.017
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