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Phospholemman and β-adrenergic stimulation in the heart

Phosphorylation at serine 68 of phospholemman (PLM) in response to β-adrenergic stimulation results in simultaneous inhibition of cardiac Na(+)/Ca(2+) exchanger NCX1 and relief of inhibition of Na(+)-K(+)-ATPase. The role of PLM in mediating β-adrenergic effects on in vivo cardiac function was inves...

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Detalhes bibliográficos
Main Authors: Wang, JuFang, Gao, Erhe, Song, Jianliang, Zhang, Xue-Qian, Li, Jifen, Koch, Walter J., Tucker, Amy L., Philipson, Kenneth D., Chan, Tung O., Feldman, Arthur M., Cheung, Joseph Y.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2838560/
https://ncbi.nlm.nih.gov/pubmed/20008271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00877.2009
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