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Phospholemman Modulates the Gating of Cardiac L-Type Calcium Channels

Ca(2+) entry through L-type calcium channels (Ca(V)1.2) is critical in shaping the cardiac action potential and initiating cardiac contraction. Modulation of Ca(V)1.2 channel gating directly affects myocyte excitability and cardiac function. We have found that phospholemman (PLM), a member of the FX...

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Detalhes bibliográficos
Main Authors: Wang, Xianming, Gao, Guofeng, Guo, Kai, Yarotskyy, Viktor, Huang, Congxin, Elmslie, Keith S., Peterson, Blaise Z.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2849072/
https://ncbi.nlm.nih.gov/pubmed/20371314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.11.032
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