Caricamento...

The Role of Flexibility in the Rational Design of Modularly Assembled Ligands Targeting the RNAs that Cause the Myotonic Dystrophies

Modularly assembled ligands were designed to target the RNAs that cause two currently untreatable neuromuscular disorders, myotonic dystrophy types 1 (DM1) and 2 (DM2). DM1 is caused by an expanded repeating sequence of CUG, and DM2 is caused by expanded CCUG repeats. Both are present in non-coding...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Disney, Matthew D., Lee, Melissa M., Pushechnikov, Alexei, Childs-Disney, Jessica L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2848078/
https://ncbi.nlm.nih.gov/pubmed/20058255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.200900716
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !