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Rational and Modular Design of Potent Ligands Targeting the RNA that Causes Myotonic Dystrophy 2
Most ligands targeting RNA are identified through screening a therapeutic target for binding members of a ligand library. A potential alternative way to construct RNA binders is through rational design using information about the RNA motifs ligands prefer to bind. Herein, we describe such an approac...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2748256/ https://ncbi.nlm.nih.gov/pubmed/19348464 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb900025w |
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