Redox-Mediated Reciprocal Regulation of SERCA and Na(+)/Ca(2+)-Exchanger Contributes to SR Ca(2+)-Depletion in Cardiac Myocytes

Myocardial failure is associated with increased oxidative stress and abnormal excitation-contraction coupling characterized by depletion of sarcoplasmic reticulum (SR) Ca(2+)-stores and a reduction in Ca(2+)-transient amplitude. Little is known about the mechanisms whereby oxidative stress affects C...

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Main Authors: Kuster, Gabriela M., Lancel, Steve, Zhang, Jingmei, Communal, Catherine, Trucillo, Mario P., Lim, Chee C., Pfister, Otmar, Weinberg, Ellen O., Cohen, Richard A., Liao, Ronglih, Siwik, Deborah A., Colucci, Wilson S.
Format: Artigo
Jezik:Inglês
Izdano: 2010
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2847633/
https://ncbi.nlm.nih.gov/pubmed/20132882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2010.01.038
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