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Nitroxyl enhances myocyte Ca(2+) transients by exclusively targeting SR Ca(2+)-cycling

Nitroxyl (HNO), the 1-electron reduction product of nitric oxide, improves myocardial contraction in normal and failing hearts. Here we test whether the HNO donor Angeli’s salt (AS) will change myocyte action potential (AP) waveform by altering the L-type Ca(2+) current (ICa) and contrast the contra...

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Bibliografiske detaljer
Main Authors: Kohr, Mark J, Kaludercic, Nina, Tocchetti, Carlo G, Gao, Wei Dong, Kass, David A, Janssen, Paul ML, Paolocci, Nazareno, Ziolo, Mark T
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3057191/
https://ncbi.nlm.nih.gov/pubmed/20036906
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