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Phosphodiesterase 5 Restricts NOS3/Soluble Guanylate Cyclase signaling to L-type Ca(2+) current in Cardiac Myocytes

Endothelial nitric oxide synthase (NOS3) regulates the functional response to β-adrenergic (β-AR) stimulation via modulation of the L-type Ca(2+) current (I(Ca)). However, the NOS3 signaling pathway modulating I(Ca) is unknown. This study investigated the contribution of soluble guanylate cyclase (s...

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Bibliografiske detaljer
Main Authors: Wang, Honglan, Kohr, Mark J, Traynham, Christopher J, Ziolo, Mark T
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2703689/
https://ncbi.nlm.nih.gov/pubmed/19345227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2009.03.021
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