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Phosphodiesterase 5 Restricts NOS3/Soluble Guanylate Cyclase signaling to L-type Ca(2+) current in Cardiac Myocytes
Endothelial nitric oxide synthase (NOS3) regulates the functional response to β-adrenergic (β-AR) stimulation via modulation of the L-type Ca(2+) current (I(Ca)). However, the NOS3 signaling pathway modulating I(Ca) is unknown. This study investigated the contribution of soluble guanylate cyclase (s...
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Main Authors: | , , , |
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Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
2009
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2703689/ https://ncbi.nlm.nih.gov/pubmed/19345227 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2009.03.021 |
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