Neuronal nitric oxide synthase signaling within cardiac myocytes targets phospholamban

Studies have shown that neuronal nitric oxide synthase (nNOS, NOS1) knockout mice (NOS1(−/−)) have increased or decreased contractility, but consistently have found a slowed rate of intracellular Ca(2+) ([Ca(2+)](i)) decline and relengthening. Contraction and [Ca(2+)](i) decline are determined by ma...

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Bibliographic Details
Main Authors: Wang, Honglan, Kohr, Mark J., Traynham, Christopher J., Wheeler, Debra G., Janssen, Paul M. L., Ziolo, Mark T.
Format: Artigo
Language:Inglês
Published: 2008
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2771755/
https://ncbi.nlm.nih.gov/pubmed/18400986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00367.2007
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