Effects of increased systolic Ca(2+) and phospholamban phosphorylation during β-adrenergic stimulation on Ca(2+) transient kinetics in cardiac myocytes

Previous studies demonstrated higher systolic intracellular Ca(2+) concentration ([Ca(2+)](i)) amplitudes result in faster [Ca(2+)](i) decline rates, as does β-adrenergic (β-AR) stimulation. The purpose of this study is to determine the major factor responsible for the faster [Ca(2+)](i) decline rat...

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Detalhes bibliográficos
Main Authors: Roof, Steve R., Shannon, Thomas R., Janssen, Paul M. L., Ziolo, Mark T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
Assuntos:
Cardiac Excitation and Contraction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3197371/
https://ncbi.nlm.nih.gov/pubmed/21765055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00402.2011
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