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Effects of increased systolic Ca(2+) and β-adrenergic stimulation on Ca(2+) transient decline in NOS1 knockout cardiac myocytes

We have previously shown that the main factor responsible for the faster [Ca(2+)](i) decline rate with β-adrenergic (β-AR) stimulation is the phosphorylation of phospholamban (PLB) rather than the increase in systolic Ca(2+) levels. The purpose of this study was to correlate the extent of augmentati...

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Detalhes bibliográficos
Main Authors: Roof, Steve R, Biesiadecki, Brandon J, Davis, Jonathan P, Janssen, Paul ML, Ziolo, Mark T
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3477803/
https://ncbi.nlm.nih.gov/pubmed/22960389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.niox.2012.08.077
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