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Huntington disease models and human neuropathology: similarities and differences

Huntington disease (HD) occurs only in humans. Thus, its natural pathogenesis takes place exclusively within the human brains expressing the causative, mutated protein huntingtin (mhtt). The techniques applicable to postmortem human HD brains are inadequate for investigating the cellular pathogenesi...

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Bibliografische gegevens
Hoofdauteur: Vonsattel, Jean Paul G.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2007
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2847401/
https://ncbi.nlm.nih.gov/pubmed/17978822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-007-0306-6
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