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Alzheimer disease models and human neuropathology: similarities and differences
Animal models aim to replicate the symptoms, the lesions or the cause(s) of Alzheimer disease. Numerous mouse transgenic lines have now succeeded in partially reproducing its lesions: the extracellular deposits of Aβ peptide and the intracellular accumulation of tau protein. Mutated human APP transg...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer-Verlag
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2100431/ https://ncbi.nlm.nih.gov/pubmed/18038275 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-007-0312-8 |
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