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Influence of Species Differences on the Neuropathology of Transgenic Huntington’s Disease Animal Models
Transgenic animal models have revealed much about the pathogenesis of age-dependent neurodegenerative diseases and proved to be a useful tool for uncovering therapeutic targets. Huntington’s disease is a well-characterized neurodegenerative disorder that is caused by expansion of a CAG repeat, which...
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| Veröffentlicht in: | J Genet Genomics |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5426814/ https://ncbi.nlm.nih.gov/pubmed/22749010 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jgg.2012.05.002 |
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