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Influence of Species Differences on the Neuropathology of Transgenic Huntington’s Disease Animal Models

Transgenic animal models have revealed much about the pathogenesis of age-dependent neurodegenerative diseases and proved to be a useful tool for uncovering therapeutic targets. Huntington’s disease is a well-characterized neurodegenerative disorder that is caused by expansion of a CAG repeat, which...

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Detalhes bibliográficos
Publicado no:J Genet Genomics
Main Authors: Li, Xiao-Jiang, Li, Shihua
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5426814/
https://ncbi.nlm.nih.gov/pubmed/22749010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jgg.2012.05.002
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