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Large Animal Models of Huntington’s Disease

Huntington’s disease is caused by the expansion of a polyglutamine repeat (>37 glutamines) in the disease protein huntingtin, which results in preferential neuronal loss in distinct brain regions. Mutant huntingtin causes late-onset neurological symptoms in patients in middle life, though the exp...

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Bibliografski detalji
Izdano u:Curr Top Behav Neurosci
Glavni autori: Li, Xiao-Jiang, Li, Shihua
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5426810/
https://ncbi.nlm.nih.gov/pubmed/24048953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/7854_2013_246
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