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GENETICS AND NEUROPATHOLOGY OF HUNTINGTON’S DISEASE
Huntington’s disease (HD) is an autosomal dominant progressive neurodegenerative disorder that prominently affects the basal ganglia, leading to affective, cognitive, behavioral and motor decline. The basis of HD is a CAG repeat expansion to >35 CAG in a gene that codes for a ubiquitous protein k...
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| Published in: | Int Rev Neurobiol |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2011
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4458347/ https://ncbi.nlm.nih.gov/pubmed/21907094 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/B978-0-12-381328-2.00014-6 |
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