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GENETICS AND NEUROPATHOLOGY OF HUNTINGTON’S DISEASE

Huntington’s disease (HD) is an autosomal dominant progressive neurodegenerative disorder that prominently affects the basal ganglia, leading to affective, cognitive, behavioral and motor decline. The basis of HD is a CAG repeat expansion to >35 CAG in a gene that codes for a ubiquitous protein k...

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Dades bibliogràfiques
Publicat a:Int Rev Neurobiol
Autors principals: Reiner, Anton, Dragatsis, Ioannis, Dietrich, Paula
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4458347/
https://ncbi.nlm.nih.gov/pubmed/21907094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/B978-0-12-381328-2.00014-6
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