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Role of cerebral cortex in the neuropathology of Huntington's disease

An expansion of glutamine repeats in the N-terminal domain of the huntingtin protein leads to Huntington's disease (HD), a neurodegenerative condition characterized by the presence of involuntary movements, dementia, and psychiatric disturbances. Evaluation of postmortem HD tissue indicates tha...

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Detalhes bibliográficos
Main Authors: Estrada-Sánchez, Ana M., Rebec, George V.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3575072/
https://ncbi.nlm.nih.gov/pubmed/23423362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncir.2013.00019
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